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Inform patients of the warning signs and symptoms of hepatotoxicitye.gnauseafatiguelethargydiarrheapruritusjaundiceright upper quadrant tendernessandflu-likesymptomsIf clinical signs and symptoms consistent with liver disease developor if systemic manifestations occure.geosinophiliarashetcdiscontinue Ponstel immediatelyand perform a clinical evaluation of the patient.

Kidney function declines as you grow olderThis medication is removed by the kidneysThereforecaution is advised when using this drug in the elderly because they may be more sensitive to its side effectsespecially stomach bleeding and kidney problems.

Advise the patient to read the FDA-approved patient labelingMedication Guidethat accompanies each prescription dispensedInform patientsfamilies and their caregivers of the following information before initiating therapy with Ponstel and periodically during the course of ongoing therapy.

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